General
   Main page   
   FTP site   

Software
   CPDL   

Research Projects
   FACE   
   SP-GSTs   
   SACO   
   GSTs   
   NHEJ SNPs   
   Vector Development   

Sequencing projects
   B. Burgdorferi   
   R. Metallidurans   
   Clostridium BC1   

Around BNL
   Biology Dept.   
   BNL   
   BNL directory   

Biology Resources
   Genome Centers   
   Databases   
   Software   
   Miscellany   
   Links   
            
SACO - Serial Analysis of Chromatin Occupancy

SACO is an application of GSTs to identify genomic locations of ChIP-isolated DNA fragments. It is a general method for conducting full-genome surveys of DNA-binding proteins.

CREB Pilot Project

SACO has been used to conduct a genome-wide survey of the CREB regulon in rat.

The CREB SACO publication is now online at Cell.
Defining the CREB Regulon: A Genome-Wide Analysis of Transcription Factor Regulatory Regions
Soren Impey, Sean R. McCorkle, Hyunjoo Cha-Molstad, Jami M. Dwyer, Gregory S. Yochum, Jeremy M. Boss, Shannon McWeeney, John J. Dunn, Gail Mandel, and Richard H. Goodman
Cell, Vol 119, 1041-1054, 29 December 2004

SACO Software

README
SACO_0.2.tar.gz

Links

SACO at the Vollum Institute, OHSU

Last updated 3:46 am, Mar 11, 2005
Maintained by Sean R. McCorkle (mccorkle@bnl.gov).

DOE/BNL Privacy & Security Notice